Seeking Health

Glutathione Plus Capsules


Size: 60 Capsules | Serving Size: 1 Capsule | Servings per Container: 60

Key Benefits and Actions
  • Enhanced glutathione formula plus nutrients for recycling and utilization
  • Taste-free, well-tolerated, and well-absorbed S-Acetyl form
  • May promote a healthy response to aging, detoxification, and strenuous physical activity

This product is not intended to diagnose, treat, cure, or prevent any disease.


Why Optimal Glutathione Plus Works

Each and every day, there are thousands of things attempting to destabilize our cells from both inside and outside of our bodies. Chemicals from inflammation, pollutants from the environment, and cellular byproducts from energy metabolism all produce free radicals, cell damage, and a need to clear out waste. Our cells have evolved over millennia with specific tools that allow them to function in this harsh environment. One of those tools is glutathione. Glutathione is a unique substance. It is a tripeptide made of three amino acids: cysteine, glutamic acid, and glycine.

Glutathione has two primary functions. First, it acts as the body’s master antioxidant by neutralizing free radicals in cells. Once it does this, however, glutathione must be recycled by enzymes before it can function again.

Second, glutathione acts as a natural detoxification agent. Its unique chemical structure allows it to bind toxins and shuttle them out of the body. The only problem is, when glutathione removes toxins from the body, it is removed as well.  Optimal Glutathione Plus provides a bioavailable form of glutathione plus recycling nutrients. It is designed to help you maintain optimal levels of glutathione in your body by supporting glutathione recycling. Each taste-free, capsule contains 100 mg of glutathione as S-acetyl-L-glutathione. This lipid-like, acetylated form supports optimal absorption and utilization in the body. The capsules provide further protection from stomach acid degradation.

S-Acetyl-L-Glutathione contains an acetyl group attached to glutathione. This protects glutathione from breaking down in the GI tract, allowing for a greater amount to be absorbed. Once inside the cells, the acetyl group is removed, leaving the glutathione molecule intact and ready to act as an antioxidant. Compared to reduced glutathione, the S-acetyl form is thought to be better absorbed. The body is able to recycle glutathione to be used over and over. The natural production of glutathione produces reactive oxygen species. Helping your body reuse glutathione reduces excess oxidation associated with glutathione production. In order for your body to recycle glutathione, it requires specific nutrients. These are used as cofactors by enzymes in your glutathione recycling pathway.

Optimal Glutathione Plus contains the nutrient cofactors needed to recycle glutathione.

  • Riboflavin (cofactor for the GSR enzyme, glutathione reductase)
  • Selenium (cofactor for the GPX enzyme, glutathione peroxidase)
  • Molybdenum (cofactor involved in sulfite-sulfate conversion)

Molybdenum, a trace mineral, helps metabolize the sulfites produced during glutathione production. Reducing sulfite levels can help minimize side effects experienced from glutathione supplementation. These can include flushing, nervousness, or racing heartbeat. Molybdenum is a cofactor for the Sulfite Oxidase (SUOX) enzyme. This enzyme is responsible for converting sulfites into less problematic sulfates.

Selenium and riboflavin are cofactors for the glutathione peroxidase (GPX) and glutathione reductase (GSR) enzymes. Hydrogen peroxide is readily formed in cells all day long. The GPX enzymes facilitate its conversion into water by donating a hydrogen molecule. Once glutathione donates hydrogen to hydrogen peroxide (and other free radicals), it must be recycled back to its reduced form. This is accomplished via the GSR enzyme with riboflavin as a cofactor.

PQQ, an antioxidant-like compound, provides additional free radical support. It protects glutathione against oxidative stress that is produced during enzymatic processes. There can be multiple potential blocks in the effectiveness of glutathione supplementation. Glutathione is a vulnerable, unstable nutrient. In supplement form, it can oxidize (degrade) quickly. Your stomach acid can destroy fragile glutathione before it gets absorbed. Moreover, most glutathione pills are not bioavailable. Optimal Glutathione Plus addresses these concerns in one easy-to-take supplement.Popular with natural detoxification and MTHFR protocols, Optimal Glutathione Plus is a great option for anyone looking to optimize their glutathione status. Start feeling vibrant today with this optimally-absorbing S-acetyl form plus recycling nutrients!


Product Information & FAQ's

Who Needs Optimal Glutathione Plus

Do you want to support healthy glutathione levels? Do you get side effects from most glutathione supplements, such as flushing or racing heartbeat?

You can support healthy glutathione levels by supplementing with a bioavailable form. You can also help your body tolerate and recycle glutathione with specific nutrients.  Optimal Glutathione Plus provides a bioavailable and well-tolerated form of glutathione. Key nutrients support glutathione recycling and function.

Optimal Glutathione Plus provides a gentle serving size (100 mg) of S-acetyl-L glutathione. The taste-free capsules may also be preferred to the stronger liposomal glutathione. In order for your body to recycle glutathione, it requires specific nutrients. These act as cofactors for enzymes that convert glutathione back to its ‘reduced’ form. Only then can it act as your body’s master antioxidant. Optimal Glutathione Plus contains nutrient cofactors needed to recycle glutathione. Glutathione is the most abundant antioxidant-like compound in the human body. However, deficiency is common as it’s difficult for your body to make. It also gets used up quickly, especially upon exposure to stress or toxins.

Optimal Glutathione Plus helps you maintain healthy glutathione levels in four ways:

  • The bioavailable form of S-acetyl-L-glutathione is readily recognized and utilized by your body. This lipid-like, acetylated form protects glutathione from breaking down in the GI tract. This can allow a greater amount to reach the cells. Compared to reduced glutathione, the acetylated form is thought to be better absorbed.
  • Capsules protect fragile glutathione from being destroyed by stomach acid, digestive enzymes, and intestinal microbes. This can allow a larger amount to reach your cells. Glutathione molecules oxidize very quickly. PQQ is added to this formula to provide further protection against oxidative damage.
  • Key recycling nutrients support the body in recycling glutathione back into its active (reduced) form. These nutrient cofactors include riboflavin and selenium. Helping your body reuse glutathione reduces the oxidation associated with glutathione production.
  • Molybdenum can help reduce side effects. Some people do not tolerate supplemental glutathione, which can raise sulfite levels. As a result, they might experience flushing of the cheeks and ears, nervousness, or a racing heartbeat. Optimal Glutathione Plus includes molybdenum, a component of the SUOX enzyme. This enzyme transforms sulfites into less problematic sulfates. This can reduce symptoms associated with glutathione supplementation.

Optimal Glutathione Plus promotes healthy: 

  • Glutathione levels
  • Glutathione recycling
  • Aging and vitality
  • Exercise performance and recovery
  • Antioxidant, free-radical, and peroxide defenses
  • Stress resilience
  • Detoxification pathways
  • Histamine metabolism
  • Liver, kidneys, lungs, GI tract, and immune system function

Intense exercise decreases blood glutathione levels and generates oxidative stress. Athletes love this formula for supporting healthy performance, recovery, and endurance. Optimal Glutathione Plus offers a gentle dose, taste-free capsules, and recycling nutrients are that are well-tolerated. The lipid-like form of S-acetyl-L-glutathione provides optimal absorption and protection through your GI tract. Experience the health benefits of glutathione recycling with this targeted formula!

Other Ingredients

Vegetarian capsule (hypromellose and water), ascorbyl palmitate, and silicon dioxide.

Optimal Glutathione Plus is Free Of

Eggs, Fish, Gluten, GMO, Milk, Peanuts, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives.

Suitable For

Vegans and Vegetarians

Suggested Use

Glutathione Plus can be taken with or without food. Take 1 capsule as needed, or as directed by your healthcare professional.

How To Store Optimal Glutathione Plus

Keep closed in a cool, dry place out of reach by children.

Are there any side effects when using Optimal Glutathione Plus?

The side effects for Optimal Glutathione Plus may include:

  • Excessive sweating
  • Stomach upset
  • Yellow or orange urine
  • Muscle tenderness
  • Tremors
  • Light-headedness
  • Facial flushing
  • Liver and kidney problems
  • Diarrhea
  • Headaches
  • Anxiety
  • Insomnia
  • Irritability

Taking glutathione for extended periods has been linked with decreased levels of zinc. If you have asthma, gout, or any other medical condition, consult with your healthcare provider before considering use of this or any other product. This product is possibly unsafe when taken at higher doses than the recommended amount.

If you believe that you are experiencing any adverse reactions, please see your healthcare professional immediately and discontinue use. Each individual may react differently to any product or supplement. We always recommend that you consult with your healthcare professional prior to considering the use of this or any supplement, especially when pregnant or breastfeeding.


Consult with a qualified healthcare provider for medical advice prior to use especially if you have any medical conditions. Do not use if tamper seal is damaged. Glutathione can raise glutamate levels in the brain of some sensitive individuals.

Who is Optimal Glutathione Plus intended for?

Optimal Glutathione Plus is great for those wanting to supplement with glutathione, but have previously experienced side effects from using glutathione supplements. The processing and recycling nutrients make this formula well-tolerated. They also help your body reuse glutathione while reducing excess oxidation associated with glutathione production.* Optimal Glutathione Plus is gluten-free, dairy-free, soy-free, and egg-free. It is also free from common allergens, additives, fillers, binders, and GMO markers.

Does Optimal Glutathione Plus contain gluten or grains?

Optimal Glutathione Plus is gluten-free. Optimal Glutathione Plus does not contain grains. However, this formula contains ascorbyl palmitate which is derived in part from highly purified corn oil. Due to the processes used to manufacture the finished ingredients, the final product is free from corn proteins.

Is Optimal Glutathione Plus free from GMOs?

Testing confirms that Optimal Glutathione Plus is free from GMO markers.