Seeking Health

ProBiota HistaminX


Size: 60 Capsules | Serving Size: 1 Capsule | Servings per Container: 60

Key Benefits and Actions
  • Histamine-friendly probiotic formulated without strains known to produce high levels of histamine
  • May support microbiome balance and a healthy gut response to ingested histamine
  • May support the health of your immune system and skin

This product is not intended to diagnose, treat, cure, or prevent any disease.


Why ProBiota HistaminX Works

Histamine is metabolized in your body via your DAO (diamine oxidase) enzymes. Due to genetic variations, some individuals have slower DAO enzymes. Your DAO enzymes can also become stressed from your environment or lifestyle.

This can slow down histamine metabolism, leading to high histamine levels. DAO enzymes can be further slowed by leaky gut, alcohol, and certain drugs. Slow enzyme activity combined with high-histamine foods can cause high histamine levels in your body.

This, in turn, can lead to increased levels of inflammation and histamine intolerance in a vicious cycle. Intestinal microbes assist us in digesting foods. In the process, they may produce byproducts that either help or harm us.

Some specific bugs like Salmonella typhi have long been known to irritate the intestinal tract and increase the release of histamine in immune cells. Some organisms used as probiotics (like Lactobacillus casei and Lactobacillus d. bulgaricus) may also contribute to a build up of gut histamine levels. In someone with histamine intolerance, this may lead to a rise in histamine associated complications.

A healthy microbiome is essential to support your body’s response to histamine. Gut health can also alleviate potential stress from slowed DAO enzyme activity.

The probiotic strains found in ProBiota HistaminX help to lessen your DAO enzyme’s workload by excluding species known to produce histamine. This unique probiotic also supports a healthy response to histamine from food and a normal inflammatory response in the gut.

By lessening your DAO enzyme’s workload, you can support the efficiency of your histamine pathway.


Product Information & FAQ's

Who Needs ProBiota HistaminX

Does your histamine response get worse when using most probiotics? Do you have histamine concerns such as headaches, intestinal upset, skin issues, or heart palpitations?

Are you looking to support your gut microbiome, but aren’t sure where to start? ProBiota HistaminX is a unique probiotic supplement designed for those sensitive to histamine. It excludes strains known to produce high levels of histamine in the gut.

Most probiotic strains naturally produce histamine in the body. This can cause adverse reactions in people who struggle with excess histamine or histamine intolerance.

ProBiota HistaminX is a histamine-friendly probiotic. Unlike most probiotics, it has been meticulously formulated to exclude species of bacteria known to produce histamine. It is a great option for those struggling with histamine intolerance or looking for a probiotic that avoids producing excess histamine in the gut.

The targeted strains of bacteria are encased in a delayed-release (acid-resistant) capsule. This helps ensure the probiotics are delivered intact to your lower digestive tract, where they are needed.

If you have histamine intolerance, it may seem like the only way to avoid unpleasant side effects is to eliminate high-histamine foods altogether. However, such a restricted diet can end up depriving your body of certain nutrients. It can also make enjoying your meals an unnecessary challenge!

Your gut health is a key factor in maintaining healthy histamine levels throughout your body. With nearly 400 5-star reviews, ProBiota HistaminX is a best-seller for good reason.

Thousands of people worldwide use it every day to support healthy gut bacteria and histamine metabolism. Whether or not you struggle with histamine, ProBiota HistaminX was designed to support your daily gut health in only one capsule per day.

ProBiota HistaminX has met standards for ingredient and product quality for Probiotics in independent testing.

Other Ingredients

Microcrystalline cellulose, vegetarian capsule (hypromellose, water, gellan gum), L-leucine, and silica.

ProBiota HistaminX is Free Of

Eggs, Fish, Gluten, GMO, Milk, Peanuts, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives.

Suitable For

Vegans and Vegetarians

Suggested Use

Take 1 capsule daily with food or as directed by your healthcare professional.

How To Store ProBiota HistaminX

Refrigerate and keep tightly closed to maintain maximum potency. This product does not require an ice pack during shipping.

Are there any side effects when using ProBiota HistaminX?

Possible side effects of this supplement include:

  • Cramping
  • Gas
  • Bloating
  • Intestinal disturbances

If you believe that you are experiencing any adverse reactions, please see your healthcare provider immediately and discontinue use. Each individual may react differently to any product or supplement.

We always recommend that you consult with your healthcare professional prior to considering the use of this or any supplement, especially when pregnant or breastfeeding.


Not suitable for children under 4 years of age. Children and pregnant or lactating women should consult their healthcare professional prior to use. Keep out of reach of children.

Constipation or shifts in bowel movements may occur when first beginning a probiotic regimen. If this happens, stop taking ProBiota HistaminX until normal bowel movement occurs. If bowel movements do not return to normal, stop use and consult a healthcare professional.

ProBiota HistaminX is NOT EFFECTIVE for symptoms of immune-related food allergies, such as peanuts, shellfish, etc., or for gluten intolerance due to sensitivity or celiac disease. DAO is not absorbed and does not have systemic activity. ProBiota HistaminX does not manage or address antibody-related or IgE-related food allergies.

Who is ProBiota HistaminX intended for?

Probiota HistaminX contains probiotic species and strains that have been carefully selected to exclude those that are known to increase histamine in the gut.

The histamine-friendly species included in this formula are delivered in a delayed release (acid resistant) capsule to help ensure that the probiotics are delivered intact to the lower digestive tract.

This formula helps to support the body’s microbiome and healthy digestion, and may help support healthy metabolism of ingested histamine. ProBiota HistaminX is for individuals who wish to support healthy histamine levels while also supporting good gut health.

ProBiota HistaminX contains only probiotic species that are considered “histamine-friendly” and excludes those known to produce histamine in the gut.

Does ProBiota HistaminX contain gluten or grains?

ProBiota HistaminX is gluten-free.ProBiota HistaminX does not contain grains.

Is ProBiota HistaminX free from GMOs?

Testing verifies that ProBiota HistaminX is free from GMO markers

Do the strains in ProBiota HistaminX produce d-lactate?

None of the strains produce d-lactate. 

What strains are contained in ProBiota HistaminX, and in what amounts?

The amounts of each strain and strain numbers are proprietary. ProBiota HistaminX is 100% strain-specific to maintain consistency from lot to lot.